An update on potential treatments for MS

Around the World there is a great deal of research being conducted into MS – it’s causes and possible treatments.  Much of this research whilst steadily extending the body of knowledge about the disease is struggling to discover new effective and affordable treatments, so here is something positive about a trial of the drug ‘cladribine’ initially abandoned in 2011.

“A drug that is blocked by the EU regulatory system has now been found to improve the quality of life of people with multiple sclerosis (MS), according to a study by Queen Mary University of London (QMUL).

QMUL researchers gained access to previously unpublished clinical trial data through a Freedom of Information request to the European Medicines Agency (EMA). The European Commission is currently deciding whether to reverse its decision and grant a license for the oral preparation of the drug ‘cladribine’.”

On a longer timescale this piece of research at the University of Florida is looking at a possible ‘cure’ – though there is much work to be done before the procedure can progress to a human clinical trial.

Unique gene therapy prevents, reverses multiple sclerosis in animal model

Summary:

“Multiple sclerosis can be inhibited or reversed in mouse models using a novel gene therapy technique to suppress the immune response that induces the disease, University of Florida Health researchers have found.

By combining the transfer of a brain-protein gene with a drug used in organ transplant recipients, the researchers essentially cured mice of multiple sclerosis, resulting in near-complete remission of disease. Their findings, which the researchers said have significant potential for treating multiple sclerosis and other autoimmune disorders, are published Sept. 21 in the journal Molecular Therapy.”